Tech, ExplainedHealthtech and life sciences
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Bioinformatics data platform

Scattered biological data, made usable.

BEFORE ITAFTER ITBioinformaticsdata platformElucidataBiostate AIPARTRNA sequencing analysis+COVERSData curationHarmonisationPublic datasetsModel-ready dataDNA sequencer↗ LAB INSTRUMENTSAND INFORMATICSsends rawgene dataCell analysisand lab imaging↗ LAB INSTRUMENTSAND INFORMATICSsends cellmeasurementsData quality and enrichment↗ DATA ENGINEERINGappliescleaningrulessuppliestraining dataAI drug discoverysuppliestarget dataMolecularmodelling softwarestores theclean dataData lakehouse↗ DATA ENGINEERINGCONCEPTS IT USESGenomicsBEFORE ITAFTER ITBioinformaticsdata platformElucidataBiostate AIPARTRNAsequencing analysis+COVERSData curationHarmonisationPublicdatasetsModel-readydataDNA sequencer↗ LAB INSTRUMENTSAND INFORMATICSsends rawgene dataCell analysis andlab imaging↗ LAB INSTRUMENTSAND INFORMATICSsends cellmeasurementsData qualityand enrichment↗ DATA ENGINEERINGappliescleaningrulessuppliestraining dataAI drug discoverysuppliestarget dataMolecularmodellingsoftwarestores theclean dataData lakehouse↗ DATA ENGINEERINGCONCEPTS IT USESGenomicsBEFORE ITDNA sequencer↗ LAB INSTRUMENTS AND INFORMATICS↓ sends raw gene dataCell analysis and lab imaging↗ LAB INSTRUMENTS AND INFORMATICS↓ sends cell measurementsData quality and enrichment↗ DATA ENGINEERING↓ applies cleaning rulesBioinformatics data platformElucidataBiostate AIRNA sequencing analysis+Data curationHarmonisationPublic datasetsModel-ready dataAFTER IT↓ supplies training dataAI drug discovery↓ supplies target dataMolecular modelling software↓ stores the clean dataData lakehouse↗ DATA ENGINEERINGCONCEPTS IT USESGenomics
A bioinformatics data platform takes in the team's own sequencer data and hundreds of public studies, labels and harmonises every sample, and hands one clean table to scientists and AI models.
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A bioinformatics data platform is software that collects scattered biological and genetic data, cleans it and puts it into one consistent form, so that scientists and AI models can use it. Bioinformatics is the use of computers to study biological data, such as genes and proteins. These platforms are also called biomedical data platforms or omics data platforms. Omics is a shared name for whole-cell data such as genomics, the study of all of a cell's genes.

Why is this needed? Biological data comes from many places, in many forms. A drug company has its own experiments. Public databases hold millions more samples, uploaded by laboratories around the world. Each laboratory names its samples differently. One file says "tumour", another says "T", a third says "cancer tissue". Genes are written with old and new names. Measurements are made on different machines, so the numbers are not directly comparable. Before anyone can analyse this data together, it must be cleaned and made consistent. This cleaning is called curation, and making the formats match is called harmonisation.

Imagine a cancer research team in Mumbai that studies oral cancer, one of the most common cancers in India. The team wants to know which genes are more active in oral tumours than in healthy tissue. Its own DNA sequencer has produced data from 80 patients. Public databases hold about 400 more studies on the same cancer. The platform finds those studies. It reads each one's descriptions and labels every sample in the same way: tissue, tumour stage, smoking or tobacco use, and treatment. It converts all gene names to one standard list. It adjusts the measurements so that they can be compared. After a few weeks, the team has one table of about 9,000 samples, instead of 400 separate files. Both the scientists and their AI models can now search it.

The platform usually stores the data in a data lakehouse, one system that holds both raw files and clean tables. It applies the same ideas as general data quality software, but with biological rules. It also takes in data from laboratory instruments, such as cell analysis and imaging systems.

The clean data then goes to the discovery tools. AI drug discovery models are trained on it. Molecular modelling software uses it to choose the target protein. Some platforms also run a specific analysis, such as RNA sequencing analysis, which shows which genes are switched on in a cell. The science of reading genes is explained in genomics.

How is this different from the DNA sequencer? The sequencer is the instrument that reads the genes in a sample. The data platform does not read anything. It gathers what many sequencers and studies have already produced, and it makes those results usable together.

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